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1

The use of the scopolamine-induced cognitive impairment model to translate on-target activity for ABT-894 from rodents/monkeys to humans: Preclinical evidences

Lynne E. Rueter, Ana L. Rêlo, Marcel M. van Gaalen, Michael E. Ballard, Alvin V. Terry Jr., Jerry Buccafusco, Min Zhang

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 53 KB

english, 2011

2

Regulation of the Hypothalamic-Pituitary-Adrenocortical System in Mice Deficient for CRH Receptors 1 and 2

Preil, Jens, Müller, Marianne B., Gesing, Angela, Reul, Johannes M. H. M., Sillaber, Inge, van Gaalen, Marcel M., Landgrebe, Jobst, Holsboer, Florian, Stenzel-Poore, Mary, Wurst, Wolfgang

Journal:

Year:

2001

Language:

english

File:

PDF, 630 KB

english, 2001

3

Development of a Semimechanistic Pharmacokinetic-Pharmacodynamic Model Describing Dextroamphetamine Exposure and Striatal Dopamine Response in Rats and Nonhuman Primates following a Single Dose of Dextroamphetamine

van Gaalen, Marcel M., Schlumbohm, Christina, Folgering, Joost H., Adhikari, Saugat, Bhattacharya, Chandrali, Steinbach, Douglas, Stratford, Robert E.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

Language:

english

File:

PDF, 861 KB

english, 2019

4

Development of a non-human primate model to support CNS translational research: Demonstration with D-amphetamine exposure and dopamine response

Folgering, Joost H., Choi, Minha, Schlumbohm, Christina, van Gaalen, Marcel M., Stratford Jr., Robert E.

Journal:

Journal of Neuroscience Methods

Year:

2019

Language:

english

File:

PDF, 2.82 MB

english, 2019

5

Critical Involvement of Dopaminergic Neurotransmission in Impulsive Decision Making

Marcel M. van Gaalen, Reinout van Koten, Anton N.M. Schoffelmeer, Louk J.M.J. Vanderschuren

Journal:

Biological Psychiatry

Year:

2006

Language:

english

File:

PDF, 442 KB

english, 2006

6

Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties

Thorsten Oost, Gisela Backfisch, Swati Bhowmik, Marcel M. van Gaalen, Hervé Geneste, Wilfried Hornberger, Wilfried Lubisch, Astrid Netz, Liliane Unger, Wolfgang Wernet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 473 KB

english, 2011

7

Mechanism of Isoflavone Adsorption from Okara Extracts onto Food-Grade Resins

Méndez Sevillano, David, Jankowiak, Lena, van Gaalen, Thomas L. T., van der Wielen, Luuk A. M., Hooshyar, Nasim, van der Goot, Atze-Jan, Ottens, Marcel

Journal:

Industrial & Engineering Chemistry Research

Year:

2014

Language:

english

File:

PDF, 3.27 MB

english, 2014

8

Classic ataxia-telangiectasia: the phenotype of long-term survivors

van Os, Nienke J. H., van Deuren, Marcel, Weemaes, Corry M. R., van Gaalen, Judith, Hijdra, Helma, Taylor, Alexander M. R., van de Warrenburg, Bart P. C., Willemsen, Michèl A. A. P.

Journal:

Journal of Neurology

Year:

2019

File:

PDF, 423 KB

2019

9

NOGO-66 receptor deficient mice show slow acquisition of spatial memory task performance

Marcel M. van Gaalen, Ana L. Relo, Bernhard K. Mueller, Gerhard Gross, Mario Mezler

Journal:

Neuroscience Letters

Year:

2012

Language:

english

File:

PDF, 383 KB

english, 2012

10

Koopkracht bijstandsgerechtigden omhoog

Marcel Warnaar,Corinne van Gaalen

Journal:

Year:

2017

Language:

dutch

File:

PDF, 239 KB

dutch, 2017

11

Behavioral disinhibition requires dopamine receptor activation

Marcel M. van Gaalen, Reinhild J. Brueggeman, Patricia F. C. Bronius, Anton N. M. Schoffelmeer, Louk J. M. J. Vanderschuren

Journal:

Psychopharmacology

Year:

2006

Language:

english

File:

PDF, 217 KB

english, 2006

12

Behavioural analysis of four mouse strains in an anxiety test battery

Marcel M van Gaalen, Thomas Steckler

Journal:

Behavioural Brain Research

Year:

2000

Language:

english

File:

PDF, 1.15 MB

english, 2000

13

Effects of transgenic overproduction of CRH on anxiety-like behaviour

Marcel M. Van Gaalen, Mary P. Stenzel-Poore, Florian Holsboer, Thomas Steckler

Journal:

European Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 295 KB

english, 2002

14

11β HSD-1 inhibition reduces Aβ pathology in a mouse model of Alzheimer's disease

Van Gaalen, Marcel M., Barghorn, Stefan, Bitner, Robert S., Ebert, Ulrich, Behl, Berthold, Meyer, Axel, Mohler, Eric, Gross, Gerhard, Jacobson, Peer

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

15

Critical involvement of 5-HT2C receptor function in amphetamine-induced 50-kHz ultrasonic vocalizations in rats

Wöhr, Markus, Rippberger, Henrike, Schwarting, Rainer K. W., van Gaalen, Marcel M.

Journal:

Psychopharmacology

Year:

2015

Language:

english

File:

PDF, 2.78 MB

english, 2015

16

Trajectories of motor abnormalities in milder phenotypes of ataxia telangiectasia

van Os, Nienke J.H., Hensiek, Anke, van Gaalen, Judith, Taylor, Alexander M.R., van Deuren, Marcel, Weemaes, Corry M.R., Willemsen, Michèl A.A.P., van de Warrenburg, Bart P.C.

Journal:

Year:

2018

Language:

english

File:

PDF, 488 KB

english, 2018

17

Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression

Anton Y. Bespalov, Marcel M. van Gaalen, Irina A. Sukhotina, Karsten Wicke, Mario Mezler, Hans Schoemaker, Gerhard Gross

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 724 KB

english, 2008

18

The Vasopressin 1b Receptor Antagonist A-988315 Blocks Stress Effects on the Retrieval of Object-Recognition Memory

Barsegyan, Areg, Atsak, Piray, Hornberger, Wilfried B, Jacobson, Peer B, van Gaalen, Marcel M, Roozendaal, Benno

Journal:

Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

19

Genotype–phenotype correlations in ataxia telangiectasia patients with ATM c.3576G>A and c.8147T>C mutations

van Os, Nienke J H, Chessa, Luciana, Weemaes, Corry M R, van Deuren, Marcel, Fiévet, Alice, van Gaalen, Judith, Mahlaoui, Nizar, Roeleveld, Nel, Schrader, Christoph, Schindler, Detlev, Taylor, Alexand

Journal:

Journal of Medical Genetics

Year:

2019

Language:

english

File:

PDF, 1.23 MB

english, 2019

20

Amphetamine decreases behavioral inhibition by stimulation of dopamine D2, but not D3, receptors

van Gaalen, Marcel M., Unger, Liliane, Jongen-Rêlo, Ana-Lucia, Schoemaker, Hans, Gross, Gerhard

Journal:

Behavioural Pharmacology

Year:

2009

Language:

english

File:

PDF, 192 KB

english, 2009

21

The locus coeruleus noradrenergic system in the rat brain studied by dual-probe microdialysis

Marcel Van Gaalen, Hiroshi Kawahara, Yukie Kawahara, Ben H.C. Westerink

Journal:

Year:

1997

Language:

english

File:

PDF, 1.77 MB

english, 1997

22

Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonists

Geneste, Hervé, Bhowmik, Swati, van Gaalen, Marcel M., Hornberger, Wilfried, Hutchins, Charles W., Netz, Astrid, Oost, Thorsten, Unger, Liliane

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 763 KB

english, 2018

23

Involvement of dopamine D1and D2receptors in the nucleus accumbens core and shell in inhibitory response control

Tommy Pattij, Mieke C. W. Janssen, Louk J. M. J. Vanderschuren, Anton N. M. Schoffelmeer, Marcel M. van Gaalen

Journal:

Psychopharmacology

Year:

2007

Language:

english

File:

PDF, 347 KB

english, 2007

24

On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists

Tommy Pattij, Dustin Schetters, Anton N. M. Schoffelmeer, Marcel M. van Gaalen

Journal:

Psychopharmacology

Year:

2012

Language:

english

File:

PDF, 307 KB

english, 2012

25

Effects of the monoamine oxidase A inhibitor moclobemide on hippocampal plasticity in GR-impaired transgenic mice

Thomas Steckler, Gerhard Rammes, Magdalena Sauvage, Marcel M van Gaalen, Carla Weis, Walter Zieglgänsberger, Florian Holsboer

Journal:

Journal of Psychiatric Research

Year:

2001

Language:

english

File:

PDF, 940 KB

english, 2001

26

Affective communication in rodents

Wöhr, Markus, van Gaalen, Marcel M., Schwarting, Rainer K.W.

Journal:

Behavioural Pharmacology

Year:

2015

Language:

english

File:

PDF, 325 KB

english, 2015

27

Classic ataxia-telangiectasia: the phenotype of long-term survivors

van Os, Nienke J. H., van Deuren, Marcel, Weemaes, Corry M. R., van Gaalen, Judith, Hijdra, Helma, Taylor, Alexander M. R., van de Warrenburg, Bart P. C., Willemsen, Michèl A. A. P.

Journal:

Journal of Neurology

Year:

2019

Language:

english

File:

PDF, 423 KB

english, 2019

28

Environmental and Pharmacological Modulation of Amphetamine- Induced 50-kHz Ultrasonic Vocalizations in Rats

Rippberger, Henrike, van Gaalen, Marcel, Schwarting, Rainer, Wohr, Markus

Journal:

Current Neuropharmacology

Year:

2015

Language:

english

File:

PDF, 933 KB

english, 2015

29

5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement

van Gaalen, Marcel M., Schetters, Dustin, Schoffelmeer, Anton N. M., De Vries, Taco J.

Journal:

The International Journal of Neuropsychopharmacology

Year:

2010

Language:

english

File:

PDF, 79 KB

english, 2010

30

Een laag inkomen en hoge zorgkosten, kan dat?

Corinne van Gaalen,Marcel Warnaar

Journal:

Year:

2016

Language:

dutch

File:

PDF, 1.98 MB

dutch, 2016

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